Bergenia ligulata is a perennial herb with short, thick, fleshy and procumbent stems and very stout root stock. Leaves are ovate or round and cm long. Bergenia ligulata wall whole plant is used for kidney and bladder stones, urinary problems. (8,9,) It has been reported to exhibit various pharmacological. Pashanabheda- Bergenia ligulata (Wall.) Engl. is a small plant used in the treatment of renal calculi, retention of urine, wounds, diseases of the.

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These data indicate the antiurolithic activity in Bergenia ligulata mediated possibly through CaC 2 O 4 crystal inhibition, diuretic, hypermagneseuric and antioxidant effects and this study rationalizes its medicinal use in bergeenia. Handbook of Ayurvedic Medicinal Plants.

Asian Medical Journal ;2: Before every experiment, a prealignment of the microscope was carried out and the focus adjusted to the interface between glass and reaction solution.

Antiurolithic effect of Bergenia ligulata rhizome: an explanation of the underlying mechanisms.

It covers the information collected from scientific journals, books, theses and reports via a library and electronic search Google Scholar, Web of Science and ScienceDirect and literature available from towhich will guide in proper identification and authentication of B. This ex vivo protocol can be used for analysis of the antiurolithiasis potential of B. Top of Page Home. Agarwal and Kumar have patented an improved process for isolation of bergenin from Bergenia species Hence comprehensive scientific knowledge would help in proper identification of present plant.


However, hepatoprotective mechanism is still unclear. Antiurolithiasis Activity of B.

Acute toxicity study Acute toxicity studies were carried out for alcoholic extract of B. The supernatant was subjected to analysis for calcium, oxalate, uric acid, and phosphate by using various biochemical kits Span Diagnostics Ltd. Screening of Nepalese medicinal plants for antiviral activity. A simple TLC method has been developed for the simultaneous quantification of bergenin, catechin and gallic acid from different parts of B.

Bergenia ligulata – Asmabhedaka

Antibacterial activity of ligullata Indian Medicinal Plants. Vijay D, Haleshi C: The method was developed in toluene: Journal of Ethnopharmacology ; Bergenin and gallic acid are the most important bioactive constituents of B.

A total of 5. Paashanbheda in different regions Table 1 3, 4, 5. In the control condition, the size of the crystals was gradually increased 3.

The mother extract and DCM fraction alone treated significantly decreased the number and size of calcium oxalate deposits in different parts of renal tubules and also reduced damage to the renal tubules.

Journal of Natural Remedies ; 3: These studies revealed antidiabetic potential of B. View at Google Scholar B.


Bergenia Ligulata Root Extract | THREE

Cardiotoxic, antidiuretic and CNS depressant action of B. A comprehensive review on bergenin, a potential hepatoprotective and antioxidative phytoconstituent. Catechin was found in both mother extract and DCM fraction, for which it can protect against oxidative injury by oxalate and crystal deposition along with its protective effect against calculi formation [ 17 ].

Ikshit Sharma contributed to literature review, study design, experimental studies, data collection, and manuscript preparation. But a little amyloid deposition in red pulp and around white pulp was observed in both urolithiasis and drug treated groups but it was lesser in extract treated rat as compared to urolithiasis rat.

Bergenia ligulata – Wikipedia

Indexed in Science Citation Index Expanded. Pharmacognostic finger print profile of a controversial drug Paashanabheda. Alpha-glucosidase inhibitor from Bergenia ligulata.

Animals were divided into six different groups, each containing six animals. Low doses of B. The administration of B. Journal of Pharmacy Research ;2: Most of the previous studies were performed on its preventive effect but we investigated the curative properties of the mother as well bioactivity guided fraction of B.