Cogan-Reese syndrome is a clinical variant of iridocorneal endothelial (ICE) syndrome (see this term) characterized by variable iris atrophy, pigmented and. This variant of ICE syndrome is distinguised by its Cogan-Reese sub-type of ICE syndrome. A YEAR-OLD woman was first diagnosed as having iridocorneal endothelial syndrome in She underwent a trabeculectomy in Photographs first.
|Published (Last):||25 February 2005|
|PDF File Size:||12.18 Mb|
|ePub File Size:||7.17 Mb|
|Price:||Free* [*Free Regsitration Required]|
A sector iridectomy, which was performed at the time of GDI in our patient, should be considered in order to eliminate the tube being pulled or clogged by ICE-related membranes. This page was last modified on April 19,at The colored nodules characteristic of Cogan-Reese Syndrome do not usually cogam in essential iris atrophy. Three weeks prior to her presentation at UIHC, she presented to her local optometrist for evaluation of blurring of her vision OS. Iris nevus Cogan-Reese syndrome.
The patient had a “beaten metal” appearance of the corneal endothelium, which is classically seen in ICE syndromes. Specular microscopy is an important diagnostic tool, as the corneal endothelium has a characteristic appearance in ICE syndrome patients.
Ophthalmology and Resee Sciences. Get free access to newly published articles Create a personal account or sign in to: Cogan-Reese Syndrome is a rare iridocorneal endothelial syndrome that most commonly affects young- to middle-aged women. Central Humphrey visual field, OU.
Asymmetric endothelial cell loss and atypical endothelial cell morphology is typically evident, which appears on a specular photomicrograph as dark, larger than normal endothelial cells, with a bright central spot.
Transmission and Scanning Electron Microscopic examination of these cells has demonstrated a population of well-differentiated cells with epithelial features such syndro,e desmosomes, tonofilaments, and microvilli. Iris nevus Cogan-Reese syndrome.
The optic disc of the left eye had a cup of 0. It presents as a unilateral disease, more common in women, between the syndromd of 20 and Am J Ophthalmol ; At that visit, her IOP was 57 mmHg, and there was evidence of anterior chamber inflammation.
Laser surgery is rarely effective. Glaucomas associated with disorders of the corneal endothelium. A Cause of Unilateral Glaucoma. Donald Abrams and Dr.
Rare Disease Database
Routine evaluation for glaucoma in these patients should be done by measuring intraocular pressure and evaluating the angle for PAS with gonioscopy. Alterations of the corneal endothelium. The congenital cataracts, optic nerve and foveal hypoplasia, bilateral presentation, lack of corneal endothelial changes, and congenital nature differentiate aniridia from ICE syndrome. The cause of Cogan-Reese syndrome is not known. These visual fields represent a significant syndromw OS despite having two prior trabeculectomies.
Iridocorneal Endothelial Syndrome and Secondary Glaucoma
A trabeculectomy with antifibrotic agents mitomycin-C or 5-fluorouracil or a glaucoma drainage device aqueous shunt have been found to be effective in controling IOP in ICE syndrome patients.
Additionally, treatment of corneal edema and other corneal changes is vital to maintain high quality visual acuity. Purchase access Subscribe to JN Learning for one year. ICE syndrome is considered sporadic in presentation, with no consistent association to other ocular or systemic disease, and familial cases have been very rare.
The histopathology of the iridocorneal-endothelial syndrome. Causes The cause of Cogan-Reese syndrome is not known. Correctopia, polycoria, ectropion uveae, posterior embryotoxon, and increased intraocular pressure are common ophthalmologic findings with ARS. Typically this is done with diode syndrlme cyclophotocoagulation diode CPCand is reserved for intractable cases of glaucoma.
Cogan-Reese Syndrome. | Cornea | JAMA Ophthalmology | JAMA Network
Pathol Biol Paris ;61 2: The corneal endothelium in ICE syndrome is typically described as “hammered silver” or “beaten bronze” in appearance when viewed through the slit lamp using specular reflection Figure 4A .
Surgical results in iridocorneal endothelial syndrome. The matted appearance of the iris and development of nodules on the iris distinguish Cogan-Reese syndrome from the other iridocorneal endothelial syndromes. The mechanism of glaucoma in ICE syndrome all three variants is believed to be related to a cellular membrane secreted by the abnormal endothelial cells.
Additionally, topical hypertonic saline solutions and gels can be utilized to improve cogaj edema by dehydrating the cornea. Glaucoma associated with iridocorneal endothelial syndrome in Indian subjects. Secondary, unilateral angle-closure glaucoma can occur in these patients because of the occlusion of the trabecular meshwork by the abnormal endothelial proliferation or PAS . Article Tools Print this article. Contraction of corneal endothelial cells that have advanced on to the iris can result in these degnerative changes.
Many had corneal edema, and all had changes in the iris consisting of one or more of the following: Get free access to newly published articles. Given syndroms IOP and worsening visual field deficits in the left eye, a Baerveldt seton implant was placed along with a surgical sector iridectomy to prevent any ICE-associated membranes from pulling the tube forward Figure 3.
Cogan-Reese Syndrome: A Rare Case of Unilateral Glaucoma
Moderate stromal edema with pigmented deposits on endothelium, most prominent inferiorly; diffuse epitheliopathy Anterior chamber: Create a free personal account to make a comment, download free article PDFs, sign up for alerts and more.
Additionally, eversion of the pupil i.
Series of 7 cases] J Fr Ophthalmol. Clinical and histopathologic finding of iris nevus Cogan-Reese syndrome. All studies receiving U.